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The TRIPS agreement was signed during the Uruguay Round of the General Agreement on Tariffs and Trade (GATT) negotiations in 1994. TRIPS stands for Trade-Related Aspects of Intellectual Property Rights and is considered one of the most significant international agreements on intellectual property rights.

The agreement seeks to balance the interests of intellectual property rights holders and the need for countries to protect public health and access to essential medicines. It also aims to promote technological innovation and the transfer of technology to developing countries, while ensuring that countries have the flexibility to adopt measures to protect public interests.

The TRIPS agreement covers various forms of intellectual property, including patents, trademarks, copyrights, trade secrets, and geographical indications. It sets out minimum standards of protection that member countries must provide to these forms of intellectual property, as well as enforcement measures to combat intellectual property theft and piracy.

The agreement has been criticized by some for creating barriers to access to essential medicines for developing countries, as it allows for the granting of patents on pharmaceutical products. However, the agreement also includes provisions for compulsory licensing and parallel importing, which allows countries to import cheaper generic versions of patented drugs.

One of the key achievements of the TRIPS agreement is the establishment of the World Trade Organization (WTO) dispute settlement mechanism, which allows member countries to file complaints against other members for alleged violations of the agreement. This mechanism has been used to resolve disputes on various intellectual property rights issues, such as patent protection for pharmaceuticals and access to generic medicines.

In conclusion, the TRIPS agreement was signed during the Uruguay Round of the GATT negotiations in 1994 and is significant in its efforts to balance the interests of intellectual property rights holders and public health concerns. While it has been criticized for creating barriers to access to essential medicines, it also includes provisions for compulsory licensing and parallel importing to address this issue. The establishment of the WTO dispute settlement mechanism is also a significant achievement of the agreement, as it has been used to resolve various disputes on intellectual property rights issues.